Abuse of methamphetamine and cocaine may enhance HIV associated neurotoxicity
نویسندگان
چکیده
منابع مشابه
Impact of cocaine abuse on HIV pathogenesis
Over 1.2 million people in the United States are infected with the human immunodeficiency virus type 1 (HIV-1). Tremendous progress has been made over the past three decades on many fronts in the prevention and treatment of HIV-1 disease. However, HIV-1 infection is incurable and antiretroviral drugs continue to remain the only effective treatment option for HIV infected patients. Unfortunately...
متن کاملDrugs of Abuse in HIV infection and neurotoxicity
HIV is a neurotropic virus that enters the brain right after infection. In the brain, HIV replicates in macrophages, microglia and small number of astrocytes (4.7 ± 2.8% in vitro and 8.2 ± 3.9 in vivo) (Eugenin et al., 2011) causing inflammatory and neurotoxic host responses. Severe neurological disorders caused by HIV are collectively known as HIV-associated neurocognitive disorders (HAND). HA...
متن کاملMethamphetamine abuse.
Methamphetamine is a stimulant commonly abused in many parts of the United States. Most methamphetamine users are white men 18 to 25 years of age, but the highest usage rates have been found in native Hawaiians, persons of more than one race, Native Americans, and men who have sex with men. Methamphetamine use produces a rapid, pleasurable rush followed by euphoria, heightened attention, and in...
متن کاملCerebral Vasculitis Associated With Cocaine Abuse
Background: Earlier reports of cocaine-associated cerebral vasculitis have been based primarily on angiographic findings without pathological verification. Case Description: We present a case of acute encephalopathy following intravenous and intranasal administration of cocaine. Brain biopsy revealed vascular changes involving primarily small arteries. Findings included lymphocytic infiltration...
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ژورنال
عنوان ژورنال: Archives of Clinical Neuropsychology
سال: 1999
ISSN: 0887-6177,1873-5843
DOI: 10.1093/arclin/14.1.130